![Anti-CD326/EPCAM nanobody [SAA1341] (STJN000163)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200776/412958/STJN000163-SDS-PAGE-1__42706.1749232486.jpg?c=1 "Anti-CD326/EPCAM nanobody [SAA1341] (STJN000163)")
![Anti-CD326/EPCAM nanobody [SAA1341] (STJN000163)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200776/412958/STJN000163-SDS-PAGE-1__42706.1749232486.jpg?c=1 "Anti-CD326/EPCAM nanobody [SAA1341] (STJN000163)")
Anti-CD326/EPCAM nanobody [SAA1341] (STJN000163)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Epithelial Cell Adhesion Molecule is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1341 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | EPCAM |
| Gene ID | 4072 |
| Uniprot ID | EPCAM_HUMAN |
Additional Info
| Post Translational Modifications | Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability. |
| Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
| Protein Name | Epithelial Cell Adhesion MoleculeEp-CamAdenocarcinoma-Associated AntigenCell Surface Glycoprotein Trop-1Epithelial Cell Surface AntigenEpithelial GlycoproteinEgpEpithelial Glycoprotein 314Egp314Hegp314Ks 1/4 AntigenKsaMajor Gastrointestinal Tumor-Associated Protein Ga733-2Tumor-Associated Calcium Signal Transducer 1Cd Antigen Cd326 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Lateral Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionColocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
| Alternative Nanobody Names | Anti-Epithelial Cell Adhesion Molecule nanobodyAnti-Ep-Cam nanobodyAnti-Adenocarcinoma-Associated Antigen nanobodyAnti-Cell Surface Glycoprotein Trop-1 nanobodyAnti-Epithelial Cell Surface Antigen nanobodyAnti-Epithelial Glycoprotein nanobodyAnti-Egp nanobodyAnti-Epithelial Glycoprotein 314 nanobodyAnti-Egp314 nanobodyAnti-Hegp314 nanobodyAnti-Ks 1/4 Antigen nanobodyAnti-Ksa nanobodyAnti-Major Gastrointestinal Tumor-Associated Protein Ga733-2 nanobodyAnti-Tumor-Associated Calcium Signal Transducer 1 nanobodyAnti-Cd Antigen Cd326 nanobodyAnti-EPCAM nanobodyAnti-GA733-2 nanobodyAnti-M1S2 nanobodyAnti-M4S1 nanobodyAnti-MIC18 nanobodyAnti-TACSTD1 nanobodyAnti-TROP1 nanobody |
Information sourced from Uniprot.org