Anti-CD326/EpCAM antibody [SRM14814] (STJ11109544)

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STJ11109544
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Host: Rabbit
Applications: WB/IF-P/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14814
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:3000-1:12000
IF-P, 1:200-1:2000
IHC-P, 1:500-1:5000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Epcam
Gene ID: 17075
Uniprot ID: EPCAM_MOUSE
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Post Translational Modifications Glycosylation at Asn-198 is crucial for protein stability.
Function May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Protein Name Epithelial Cell Adhesion Molecule
Ep-Cam
Epithelial Glycoprotein 314
Egp314
Megp314
Protein 289a
Tumor-Associated Calcium Signal Transducer 1
Cd Antigen Cd326
Database Links Reactome: R-MMU-202733
Cellular Localisation Lateral Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Tight Junction
Colocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction
Alternative Antibody Names Anti-Epithelial Cell Adhesion Molecule antibody
Anti-Ep-Cam antibody
Anti-Epithelial Glycoprotein 314 antibody
Anti-Egp314 antibody
Anti-Megp314 antibody
Anti-Protein 289a antibody
Anti-Tumor-Associated Calcium Signal Transducer 1 antibody
Anti-Cd Antigen Cd326 antibody
Anti-Epcam antibody
Anti-Tacstd1 antibody

Information sourced from Uniprot.org