Anti-CD320 antibody (100-180 aa) (STJ190275)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 100-180
General Information
| Short Description | Rabbit polyclonal anti-CD320 antigen (100-180 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD320 |
| Gene ID | 51293 |
| Uniprot ID | CD320_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 100-180 |
| Immunogen Region | 100-180 aa |
| Specificity | CD320 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Receptor for transcobalamin saturated with cobalamin (TCbl). Plays an important role in cobalamin uptake. Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells. Functions as costimulator to promote B cell responses to antigenic stimuli.promotes B cell differentiation and proliferation. Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. |
| Protein Name | Cd320 Antigen8d6 AntigenFdc-Signaling Molecule 8d6Fdc-Sm-8d6Transcobalamin ReceptorTcblrCd Antigen Cd320 |
| Database Links | Reactome: R-HSA-3359485Reactome: R-HSA-9758890 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd320 Antigen antibodyAnti-8d6 Antigen antibodyAnti-Fdc-Signaling Molecule 8d6 antibodyAnti-Fdc-Sm-8d6 antibodyAnti-Transcobalamin Receptor antibodyAnti-Tcblr antibodyAnti-Cd Antigen Cd320 antibodyAnti-CD320 antibodyAnti-8D6A antibodyAnti-UNQ198 antibodyAnti-PRO224 antibody |
Information sourced from Uniprot.org