• Human peripheral blood lymphocytes were stained with Anti-CD32 antibody (STJA0000405) (filled gray histogram). Unstained lymphocytes (empty black histogram) were used as control.

Anti-CD32/FCGR2B antibody [IV-3] {APC} (STJA0000405)

SKU:
STJA0000405

£157.50 - £394.50
Current Stock:
Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Low affinity immunoglobulin gamma Fc region receptor II-b is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: IV-3
Conjugation: APC
Isotype: IgG2bk
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: FCGR2B
Gene ID: 2213
Uniprot ID: FCG2B_HUMAN
Tissue Specificity Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
Post Translational Modifications Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.
Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B
Igg Fc Receptor Ii-B
Cdw32
Fc-Gamma Rii-B
Fc-Gamma-Riib
Fcrii-B
Cd Antigen Cd32
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B antibody
Anti-Igg Fc Receptor Ii-B antibody
Anti-Cdw32 antibody
Anti-Fc-Gamma Rii-B antibody
Anti-Fc-Gamma-Riib antibody
Anti-Fcrii-B antibody
Anti-Cd Antigen Cd32 antibody
Anti-FCGR2B antibody
Anti-CD32 antibody
Anti-FCG2 antibody
Anti-IGFR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance