Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A antibodyAnti-Igg Fc Receptor Ii-A antibodyAnti-Cdw32 antibodyAnti-Fc-Gamma Rii-A antibodyAnti-Fc-Gamma-Riia antibodyAnti-Fcrii-A antibodyAnti-Cd Antigen Cd32 antibodyAnti-FCGR2A antibodyAnti-CD32 antibodyAnti-FCG2 antibodyAnti-FCGR2A1 antibodyAnti-IGFR2 antibody |
Information sourced from Uniprot.org