Host: |
Mouse |
Applications: |
IHC-P |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-CD31 is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
JC70 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1k |
Formulation: |
Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Dilution Range: |
IHC 1: 25 – 1:100 |
Storage Instruction: |
Store at 2-8°C upon receipt. |
Background | CD31 has cytoplasmic, membranous expression in non-neoplastic and neoplastic vascular endothelial cells.1 It has been used as a tool to identify the vascular origin of neoplasms such as angiosarcomas, Kaposi sarcomas and epithelioid hemangioendothelioma. Immunohistochemical study with CD31 has also been shown useful to detect areas of tumor lymphovascular invasion. Additionally, detection of weak diffuse cytoplasmic CD31 immunoreactivity has been seen in cases of various carcinomas with occasional membranous staining in ductal carcinomas of the breast as well as in intratumoral macrophages. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance