Anti-CD31 antibody [JC70] (STJ16100335)

Anti-CD31 antibody [JC70] (STJ16100335)

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STJ16100335
£557.50 - £836.50
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-CD31 is suitable for use in Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : JC70
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Dilution Range: IHC 1: 25 – 1:100
Storage Instruction: Store at 2-8°C upon receipt.
Background CD31 has cytoplasmic, membranous expression in non-neoplastic and neoplastic vascular endothelial cells.1 It has been used as a tool to identify the vascular origin of neoplasms such as angiosarcomas, Kaposi sarcomas and epithelioid hemangioendothelioma. Immunohistochemical study with CD31 has also been shown useful to detect areas of tumor lymphovascular invasion. Additionally, detection of weak diffuse cytoplasmic CD31 immunoreactivity has been seen in cases of various carcinomas with occasional membranous staining in ductal carcinomas of the breast as well as in intratumoral macrophages.

Information sourced from Uniprot.org

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