Anti-CD292/BMPR1A antibody [AbD1556] {APC} (STJA0029402)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationAPC
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal Bone Morphogenetic Protein Receptor Type-1a antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AbD1556 |
| Isotype | IgG1k |
| Conjugation | APC |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | BMPR1A |
| Gene ID | 657 |
| Uniprot ID | BMR1A_HUMAN |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2. |
| Protein Name | Bone Morphogenetic Protein Receptor Type-1aBmp Type-1a ReceptorBmpr-1aActivin Receptor-Like Kinase 3Alk-3Serine/Threonine-Protein Kinase Receptor R5Skr5Cd Antigen Cd292 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell Surface |
| Alternative Antibody Names | Anti-Bone Morphogenetic Protein Receptor Type-1a antibodyAnti-Bmp Type-1a Receptor antibodyAnti-Bmpr-1a antibodyAnti-Activin Receptor-Like Kinase 3 antibodyAnti-Alk-3 antibodyAnti-Serine/Threonine-Protein Kinase Receptor R5 antibodyAnti-Skr5 antibodyAnti-Cd Antigen Cd292 antibodyAnti-BMPR1A antibodyAnti-ACVRLK3 antibodyAnti-ALK3 antibody |
Information sourced from Uniprot.org