Anti-CD28 antibody [CD28.2] (STJA0002113)

SKU:
STJA0002113

£96.50 - £122.50
Current Stock:
Host: Mouse
Applications: FC/IHC/IP
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-T-cell-specific surface glycoprotein CD28 is suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: CD28.2
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300
Concentration: 0.5 mg/mL
Storage Instruction: Store at 2-8°C. Do not freeze this product.
Gene Symbol: CD28
Gene ID: 940
Uniprot ID: CD28_HUMAN
Tissue Specificity Expressed in T-cells and plasma cells, but not in less mature B-cells.
Post Translational Modifications CD40LG induces tyrosine phosphorylation of isoform 3.
Function Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells.
Protein Name T-Cell-Specific Surface Glycoprotein Cd28
Tp44
Cd Antigen Cd28
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-164939
Reactome: R-HSA-2219530
Reactome: R-HSA-389356
Reactome: R-HSA-389357
Reactome: R-HSA-389359
Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Surface
Alternative Antibody Names Anti-T-Cell-Specific Surface Glycoprotein Cd28 antibody
Anti-Tp44 antibody
Anti-Cd Antigen Cd28 antibody
Anti-CD28 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance