![Anti-CD273/PD-L2/PDCD1LG2 nanobody [SAA1281] (STJN000298)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200911/413093/STJN000298-SDS-PAGE-1__77713.1749232596.jpg?c=1 "Anti-CD273/PD-L2/PDCD1LG2 nanobody [SAA1281] (STJN000298)")
![Anti-CD273/PD-L2/PDCD1LG2 nanobody [SAA1281] (STJN000298)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200911/413093/STJN000298-SDS-PAGE-1__77713.1749232596.jpg?c=1 "Anti-CD273/PD-L2/PDCD1LG2 nanobody [SAA1281] (STJN000298)")
Anti-CD273/PD-L2/PDCD1LG2 nanobody [SAA1281] (STJN000298)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Programmed Cell Death 1 Ligand 2 is suitable for use in ELISA, Flow Cytometry and SPR research applications. |
| Applications | ELISA/FC/SPR |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1281 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | PDCD1LG2 |
| Gene ID | 80380 |
| Uniprot ID | PD1L2_HUMAN |
Additional Info
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
| Database Links | Reactome: R-HSA-389948 |
| Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
| Alternative Nanobody Names | Anti-Programmed Cell Death 1 Ligand 2 nanobodyAnti-Pd-1 Ligand 2 nanobodyAnti-Pd-L2 nanobodyAnti-Pdcd1 Ligand 2 nanobodyAnti-Programmed Death Ligand 2 nanobodyAnti-Butyrophilin B7-Dc nanobodyAnti-B7-Dc nanobodyAnti-Cd Antigen Cd273 nanobodyAnti-PDCD1LG2 nanobodyAnti-B7DC nanobodyAnti-CD273 nanobodyAnti-PDCD1L2 nanobodyAnti-PDL2 nanobody |
Information sourced from Uniprot.org