| Host: | Rat |
| Applications: | Block/Depletion/FC/IHC/IP |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rat monoclonal antibody anti-Interleukin-2 receptor subunit alpha is suitable for use in Universal, Universal, Flow Cytometry, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | PC-61.5.3 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | 0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at 2-8°C. Do not freeze this product. |
| Gene Symbol: | Il2ra |
| Gene ID: | 16184 |
| Uniprot ID: | IL2RA_MOUSE |
| Function | Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. |
| Protein Name | Interleukin-2 Receptor Subunit AlphaIl-2 Receptor Subunit AlphaIl-2-RaIl-2r Subunit AlphaIl2-RaP55Cd Antigen Cd25 |
| Database Links | Reactome: R-MMU-5673001Reactome: -MMU-9020558Reactome: -MMU-912526 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-2 Receptor Subunit Alpha antibodyAnti-Il-2 Receptor Subunit Alpha antibodyAnti-Il-2-Ra antibodyAnti-Il-2r Subunit Alpha antibodyAnti-Il2-Ra antibodyAnti-P55 antibodyAnti-Cd Antigen Cd25 antibodyAnti-Il2ra antibodyAnti-Il2r antibody |
Information sourced from Uniprot.org
![C57BL/6 murine splenocytes were stained with Anti-CD25 antibody (STJA0000575) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD4 Monoclonal Antibody (FITC Conjugated). Splenocytes stained with Anti-Mouse CD4 Monoclonal Antibody (FITC Conjugated)and Rat IgG1 Isotype Control (AF647 Conjugated) (right) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/145428/292089/STJA0000575_1__28946.1631205919.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-CD25 antibody (STJA0000575) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD4 Monoclonal Antibody (FITC Conjugated). Splenocytes stained with Anti-Mouse CD4 Monoclonal Antibody (FITC Conjugated)and Rat IgG1 Isotype Control (AF647 Conjugated) (right) were used as control.")
![C57BL/6 murine splenocytes were stained with Anti-CD25 antibody (STJA0000569) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD4 Monoclonal Antibody (APC Conjugated) (right)). Splenocytes stained with Anti-Mouse CD4 Monoclonal Antibody (APC Conjugated).are used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/145422/292083/STJA0000569_1__41903.1631205912.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-CD25 antibody (STJA0000569) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD4 Monoclonal Antibody (APC Conjugated) (right)). Splenocytes stained with Anti-Mouse CD4 Monoclonal Antibody (APC Conjugated).are used as control.")