Anti-CD24 antibody [SAA2212] (STJA0031780)

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STJA0031780
£254.50 - £378.50
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Host: Human
Applications: ELISA/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Human monoclonal antibody anti-Signal Transducer Cd24 is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA2212
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: 0.01M PBS, pH 7.4, 0.09% Sodium azide.
Purification: Protein A/G purified from cell culture supernatant.
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CD24
Gene ID: 100133941
Uniprot ID: CD24_HUMAN
Post Translational Modifications Extensively O-glycosylated.
Function May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Protein Name Signal Transducer Cd24
Small Cell Lung Carcinoma Cluster 4 Antigen
Cd Antigen Cd24
Database Links Reactome: R-HSA-373760
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Signal Transducer Cd24 antibody
Anti-Small Cell Lung Carcinoma Cluster 4 Antigen antibody
Anti-Cd Antigen Cd24 antibody
Anti-CD24 antibody
Anti-CD24A antibody

Information sourced from Uniprot.org