• Human peripheral blood lymphocytes were stained with Anti-CD24 antibody (STJA0000921) (filled gray histogram). Unstained lymphocytes (empty black histogram) were used as control.

Anti-CD24 antibody [mL5] {PerCP/Cyanine5.5} (STJA0000921)

SKU:
STJA0000921

£166.50 - £451.50
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Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Signal transducer CD24 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: mL5
Conjugation: PerCP/Cyanine5.5
Isotype: IgG2ak
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: CD24
Gene ID: 100133941
Uniprot ID: CD24_HUMAN
Tissue Specificity B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells.
Post Translational Modifications Extensively O-glycosylated.
Function May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Protein Name Signal Transducer Cd24
Small Cell Lung Carcinoma Cluster 4 Antigen
Cd Antigen Cd24
Database Links Reactome: R-HSA-373760
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Signal Transducer Cd24 antibody
Anti-Small Cell Lung Carcinoma Cluster 4 Antigen antibody
Anti-Cd Antigen Cd24 antibody
Anti-CD24 antibody
Anti-CD24A antibody

Information sourced from Uniprot.org

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