| Host: | Rabbit |
| Applications: | WB/FC/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Cd24 |
| Gene ID: | 12484 |
| Uniprot ID: | CD24_MOUSE |
| Immunogen Region: | 27-53 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-53 of mouse CD24 ( NP_033976.1 ). |
| Immunogen Sequence: | NQTSVAPFPGNQNISASPNP SNATTRG |
| Tissue Specificity | In lymphoid, myeloid, and erythroid cells. |
| Post Translational Modifications | The identity of the N- and O-linked polysaccharides is not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc. |
| Function | May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. |
| Protein Name | Signal Transducer Cd24 Lymphocyte Antigen 52 Ly-52 M1/69-J11d Heat Stable Antigen Hsa Nectadrin R13-Ag X62 Heat Stable Antigen Cd Antigen Cd24 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Antibody Names | Anti-Signal Transducer Cd24 antibody Anti-Lymphocyte Antigen 52 antibody Anti-Ly-52 antibody Anti-M1/69-J11d Heat Stable Antigen antibody Anti-Hsa antibody Anti-Nectadrin antibody Anti-R13-Ag antibody Anti-X62 Heat Stable Antigen antibody Anti-Cd Antigen Cd24 antibody Anti-Cd24 antibody Anti-Cd24a antibody Anti-Ly-52 antibody |
Information sourced from Uniprot.org