Anti-CD23 antibody [MHM6] (STJA0027785)

SKU:
STJA0027785
€289.38 - €426.88
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Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Low Affinity Immunoglobulin Epsilon Fc Receptor is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : MHM6
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS, pH 7.4, 0.09% Sodium azide.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: FCER2
Gene ID: 2208
Uniprot ID: FCER2_HUMAN
Post Translational Modifications N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
Protein Name Low Affinity Immunoglobulin Epsilon Fc Receptor
Blast-2
C-Type Lectin Domain Family 4 Member J
Fc-Epsilon-Rii
Immunoglobulin E-Binding Factor
Lymphocyte Ige Receptor
Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form
Database Links Reactome: R-HSA-2197563
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Lipid-Anchor
Secreted
Also Exists As A Soluble Excreted Form
Scd23
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody
Anti-Blast-2 antibody
Anti-C-Type Lectin Domain Family 4 Member J antibody
Anti-Fc-Epsilon-Rii antibody
Anti-Immunoglobulin E-Binding Factor antibody
Anti-Lymphocyte Ige Receptor antibody
Anti-Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibody
Anti-FCER2 antibody
Anti-CD23A antibody
Anti-CLEC4J antibody
Anti-FCE2 antibody
Anti-IGEBF antibody

Information sourced from Uniprot.org