Anti-CD229/LY9 antibody [SAA1619] (STJA0020047)

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STJA0020047
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-T-Lymphocyte Surface antigen Ly-9 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1619
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: LY9
Gene ID: 4063
Uniprot ID: LY9_HUMAN
Function Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion.the costimulatory activity requires SH2D1A. Promotes recruitment of RORC to the IL-17 promoter. May be involved in the maintenance of peripheral cell tolerance by serving as a negative regulator of the immune response. May disable autoantibody responses and inhibit IFN-gamma secretion by CD4(+) T-cells. May negatively regulate the size of thymic innate CD8(+) T-cells and the development of invariant natural killer T (iNKT) cells.
Protein Name T-Lymphocyte Surface Antigen Ly-9
Cell Surface Molecule Ly-9
Lymphocyte Antigen 9
Slam Family Member 3
Slamf3
Signaling Lymphocytic Activation Molecule 3
Cd Antigen Cd229
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-T-Lymphocyte Surface Antigen Ly-9 antibody
Anti-Cell Surface Molecule Ly-9 antibody
Anti-Lymphocyte Antigen 9 antibody
Anti-Slam Family Member 3 antibody
Anti-Slamf3 antibody
Anti-Signaling Lymphocytic Activation Molecule 3 antibody
Anti-Cd Antigen Cd229 antibody
Anti-LY9 antibody
Anti-CDABP0070 antibody

Information sourced from Uniprot.org