| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CD226 (19-336) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CD226 |
| Gene ID: |
10666 |
| Uniprot ID: |
CD226_HUMAN |
| Immunogen Region: |
19-336 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-336 of human CD226 (NP_006557.2). |
| Immunogen Sequence: |
EEVLWHTSVPFAENMSLECV YPSMGILTQVEWFKIGTQQD SIAIFSPTHGMVIRKPYAER VYFLNSTMASNNMTLFFRNA SEDDVGYYSCSLYTYPQGTW QKVIQVVQSDSFEAAVPSNS HIVSEPGKNVTLTCQPQMTW PVQAVRWEKIQPRQIDLLTY CNLVHGRNFTSKFPRQIVSN CSHGRWSVIVIPDVTVSDSG LYRCYLQASAGENETFVMRL TVAEGKTDNQYTLFVAGGT |
| Tissue Specificity | Expressed by peripheral blood T-lymphocytes. |
| Function | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding. |
| Protein Name | Cd226 AntigenDnax Accessory Molecule 1Dnam-1Cd Antigen Cd226 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd226 Antigen antibodyAnti-Dnax Accessory Molecule 1 antibodyAnti-Dnam-1 antibodyAnti-Cd Antigen Cd226 antibodyAnti-CD226 antibodyAnti-DNAM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
