| Post Translational Modifications | N-glycosylated. N-linked glycosyl chains contribute to ligand recognition and intra-receptor interactions required for formation of an active ternary receptor complex. |
| Function | Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3. |
| Protein Name | Interleukin-18 Receptor 1Il-18r-1Il-18r1Cd218 Antigen-Like Family Member ACdw218aIl1 Receptor-Related ProteinIl-1rrpIl1r-RpInterleukin-18 Receptor AlphaIl-18r-AlphaIl-18ralphaCd Antigen Cd218a |
| Database Links | Reactome: R-HSA-9008059Reactome: R-HSA-9012546 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-18 Receptor 1 antibodyAnti-Il-18r-1 antibodyAnti-Il-18r1 antibodyAnti-Cd218 Antigen-Like Family Member A antibodyAnti-Cdw218a antibodyAnti-Il1 Receptor-Related Protein antibodyAnti-Il-1rrp antibodyAnti-Il1r-Rp antibodyAnti-Interleukin-18 Receptor Alpha antibodyAnti-Il-18r-Alpha antibodyAnti-Il-18ralpha antibodyAnti-Cd Antigen Cd218a antibodyAnti-IL18R1 antibodyAnti-IL1RRP antibody |
Information sourced from Uniprot.org
