Anti-CD213a2/IL-13 R alpha 2 antibody [SRM14953] (STJ11109683)

SKU:
STJ11109683
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Host: Rabbit
Applications: WB/IP/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14953
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:5000-1:20000
IP, 0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL13RA2
Gene ID: 3598
Uniprot ID: I13R2_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Post Translational Modifications Cleaved by MMP8 leading to a soluble form that is also able to interact with IL13.
Function Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1.
Protein Name Interleukin-13 Receptor Subunit Alpha-2
Il-13 Receptor Subunit Alpha-2
Il-13r Subunit Alpha-2
Il-13r-Alpha-2
Il-13ra2
Interleukin-13-Binding Protein
Cd Antigen Cd213a2
Database Links Reactome: R-HSA-6785807
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-13 Receptor Subunit Alpha-2 antibody
Anti-Il-13 Receptor Subunit Alpha-2 antibody
Anti-Il-13r Subunit Alpha-2 antibody
Anti-Il-13r-Alpha-2 antibody
Anti-Il-13ra2 antibody
Anti-Interleukin-13-Binding Protein antibody
Anti-Cd Antigen Cd213a2 antibody
Anti-IL13RA2 antibody
Anti-IL13R antibody

Information sourced from Uniprot.org