| Tissue Specificity | Expressed in skin, spleen and lung, probably in a subset of dendritic cells. Detected in spleen extrafollicular paracortical areas including the red pulp and marginal zones, and at lower levels, in the follicular area. Detected in skin suprabasal areas adjacent to the epidermis and in epidermal cell layer. |
| Function | Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. |
| Protein Name | Cd209 Antigen-Like Protein BDc-Sign-Related Protein 1Dc-Signr1Otb7Cd Antigen Cd209 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Cd209 Antigen-Like Protein B antibodyAnti-Dc-Sign-Related Protein 1 antibodyAnti-Dc-Signr1 antibodyAnti-Otb7 antibodyAnti-Cd Antigen Cd209 antibodyAnti-Cd209b antibody |
Information sourced from Uniprot.org
