Host: | Rat |
Applications: | ELISA/FC |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rat monoclonal antibody anti-C-Type Lectin Domain Family 4 Member K is suitable for use in ELISA and Flow Cytometry research applications. |
Clonality : | Monoclonal |
Clone ID : | 4C7 |
Conjugation: | Unconjugated |
Isotype: | IgG1k |
Formulation: | 0.01M PBS, pH 7.4. |
Purification: | Protein A/G purified from cell culture supernatant. |
Concentration: | 1 mg/ml |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | Cd207 |
Gene ID: | 246278 |
Uniprot ID: | CLC4K_MOUSE |
Function | Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs).is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. |
Protein Name | C-Type Lectin Domain Family 4 Member KLangerinCd Antigen Cd207 |
Database Links | Reactome: R-MMU-1236978 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinFound In Birbeck Granules (Bgs)Which Are Organelles Consisting Of Superimposed And Zippered Membranes |
Alternative Antibody Names | Anti-C-Type Lectin Domain Family 4 Member K antibodyAnti-Langerin antibodyAnti-Cd Antigen Cd207 antibodyAnti-Cd207 antibodyAnti-Clec4k antibody |
Information sourced from Uniprot.org