Anti-CD207 antibody [2G3] (STJA0027153)

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STJA0027153
€318.13 - €473.13
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Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-C-Type Lectin Domain Family 4 Member K is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 2G3
Conjugation: Unconjugated
Isotype: IgG1L
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CD207
Gene ID: 50489
Uniprot ID: CLC4K_HUMAN
Function Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs).is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Protein Name C-Type Lectin Domain Family 4 Member K
Langerin
Cd Antigen Cd207
Database Links Reactome: R-HSA-1236978
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Found In Birbeck Granules (Bgs)
Which Are Organelles Consisting Of Superimposed And Zippered Membranes
Alternative Antibody Names Anti-C-Type Lectin Domain Family 4 Member K antibody
Anti-Langerin antibody
Anti-Cd Antigen Cd207 antibody
Anti-CD207 antibody
Anti-CLEC4K antibody

Information sourced from Uniprot.org