Western blot analysis of various lysates using CD200R1 Rabbit pAb (STJ110577) at 1:1000 dilution. <br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br/>Lysates/proteins: 25 Mu g per lane. <br/>Blocking buffer: 3% nonfat dry milk in TBST. <br/>Detection: ECL Basic Kit <br/>Exposure time: 90s.

Anti-CD200R1 antibody (249-348) (STJ110577)

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STJ110577
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD200R1
Gene ID: 131450
Uniprot ID: MO2R1_HUMAN
Immunogen Region: 249-348
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 249-348 of human CD200R1 (NP_620161.1).
Immunogen Sequence: SLYIELLPVPGAKKSAKLYI PYIILTIIILTIVGFIWLLK VNGCRKYKLNKTESTPVVEE DEMQPYASYTEKNNPLYDTT NKVKASEALQSEVDTDLHTL
Tissue Specificity Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.
Function Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Protein Name Cell Surface Glycoprotein Cd200 Receptor 1
Cd200 Cell Surface Glycoprotein Receptor
Cell Surface Glycoprotein Ox2 Receptor 1
Database Links Reactome: R-HSA-198933
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 4: Cell Membrane
Isoform 2: Secreted
Isoform 3: Secreted
Alternative Antibody Names Anti-Cell Surface Glycoprotein Cd200 Receptor 1 antibody
Anti-Cd200 Cell Surface Glycoprotein Receptor antibody
Anti-Cell Surface Glycoprotein Ox2 Receptor 1 antibody
Anti-CD200R1 antibody
Anti-CD200R antibody
Anti-CRTR2 antibody
Anti-MOX2R antibody
Anti-OX2R antibody
Anti-UNQ2522 antibody
Anti-PRO6015 antibody

Information sourced from Uniprot.org

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