Anti-CD20/MS4A1 nanobody [SAA1332] (STJN000138)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000138
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-B-Lymphocyte antigen Cd20 is suitable for use in ELISA research applications.
ApplicationsELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA1332
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1.12 mg/mL
PurificationPurified by Nickel column.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolMS4A1
Gene ID931
Uniprot IDCD20_HUMAN

Additional Info

Post Translational Modifications Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate.
Function B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Protein Name B-Lymphocyte Antigen Cd20
B-Lymphocyte Surface Antigen B1
Bp35
Leukocyte Surface Antigen Leu-16
Membrane-Spanning 4-Domains Subfamily A Member 1
Cd Antigen Cd20
Database Links
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lipid-Anchor
Constitutively Associated With Membrane Rafts
Alternative Nanobody Names Anti-B-Lymphocyte Antigen Cd20 nanobody
Anti-B-Lymphocyte Surface Antigen B1 nanobody
Anti-Bp35 nanobody
Anti-Leukocyte Surface Antigen Leu-16 nanobody
Anti-Membrane-Spanning 4-Domains Subfamily A Member 1 nanobody
Anti-Cd Antigen Cd20 nanobody
Anti-MS4A1 nanobody
Anti-CD20 nanobody

Information sourced from Uniprot.org

Citations

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