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| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CD2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | MRQ-11 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Dilution Range: | IHC 1:10-1:50 |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Tissue Specificity | Expressed in natural killer cells (at protein level). |
| Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
| Protein Name | T-Cell Surface Antigen Cd2Erythrocyte ReceptorLfa-2Lfa-3 ReceptorRosette ReceptorT-Cell Surface Antigen T11/Leu-5Cd Antigen Cd2 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Surface Antigen Cd2 antibodyAnti-Erythrocyte Receptor antibodyAnti-Lfa-2 antibodyAnti-Lfa-3 Receptor antibodyAnti-Rosette Receptor antibodyAnti-T-Cell Surface Antigen T11/Leu-5 antibodyAnti-Cd Antigen Cd2 antibodyAnti-CD2 antibodyAnti-SRBC antibody |
Information sourced from Uniprot.org
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