| Host: | Mouse |
| Applications: | WB/IHC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-T-cell surface antigen CD2 (1-100 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT-CD2 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:100-500WB 1:100-2000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD2 |
| Gene ID: | 914 |
| Uniprot ID: | CD2_HUMAN |
| Immunogen Region: | 1-100 aa |
| Specificity: | This antibody detects endogenous levels of human CD2. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH9.0 was highly recommended as antigen repair method in paraffin section |
| Immunogen: | Synthesized peptide derived from the human CD2 at the amino acid range 1-100 |
| Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
| Protein Name | T-Cell Surface Antigen Cd2Erythrocyte ReceptorLfa-2Lfa-3 ReceptorRosette ReceptorT-Cell Surface Antigen T11/Leu-5Cd Antigen Cd2 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Surface Antigen Cd2 antibodyAnti-Erythrocyte Receptor antibodyAnti-Lfa-2 antibodyAnti-Lfa-3 Receptor antibodyAnti-Rosette Receptor antibodyAnti-T-Cell Surface Antigen T11/Leu-5 antibodyAnti-Cd Antigen Cd2 antibodyAnti-CD2 antibodyAnti-SRBC antibody |
Information sourced from Uniprot.org
