| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CD1C |
| Gene ID: | 911 |
| Uniprot ID: | CD1C_HUMAN |
| Immunogen Region: | 18-300 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-300 of human CD1C (NP_001756.2). |
| Immunogen Sequence: | NADASQEHVSFHVIQIFSFV NQSWARGQGSGWLDELQTHG WDSESGTIIFLHNWSKGNFS NEELSDLELLFRFYLFGLTR EIQDHASQDYSKYPFEVQVK AGCELHSGKSPEGFFQVAFN GLDLLSFQNTTWVPSPGCGS LAQSVCHLLNHQYEGVTETV YNLIRSTCPRFLLGLLDAGK MYVHRQVRPEAWLSSRPSLG SGQLLLVCHASGFYPKPVWV TWMRNEQEQLGTKHGDILP |
| Tissue Specificity | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. |
| Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
| Protein Name | T-Cell Surface Glycoprotein Cd1cCd Antigen Cd1c |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinEndosome MembraneLysosomeSubject To Intracellular Trafficking Between The Cell Membrane And Endosomes |
| Alternative Antibody Names | Anti-T-Cell Surface Glycoprotein Cd1c antibodyAnti-Cd Antigen Cd1c antibodyAnti-CD1C antibody |
Information sourced from Uniprot.org