Anti-CD1b antibody [100-1A5] (STJ16100159)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgMk
ImmunogenA BALB/c mouse was immunized with stimulated human leucocytes. Fusion partner: NS-1.
General Information
| Short Description | Mouse monoclonal anti-CD1b for use in ELISA, FC, IF and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC/IF/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 100-1A5 |
| Isotype | IgMk |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | ELISA (solid phase: not known; tracer: 0.001-100 ยตg/ml for 30 min at RT). Flow cytometry (0.5-1.0 ยตg/million cells in 0.1 ml). Immunofluorescence (0.5-1.0 ยตg/ml). Immunohistology (1.0-2.0 ยตg/ml for 30 min at RT; an appropriate antigen retrieval metho |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8ยฐC upon receipt. |
Target Information
| Immunogen | A BALB/c mouse was immunized with stimulated human leucocytes. Fusion partner: NS-1. |
Additional Info
| Background | 100-1A5 reacts with CD1b, a 44KDa type 1 glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes and T acute lymphoblastic leukemia cells. CD1, type 1 membrane protein, has structural similarity to the MHC class 1 molecule and has been shown to present lipid antigens for recognition by T lymphocytes. CD1b is also expressed in Langerhans interdigitating cells. 100-1A5 also reacts with pyramidal cells in the brain and was typed at the IVth International CD Workshop. |
Information sourced from Uniprot.org