| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD1A (CD1a) is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | O10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:50‐100 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | CD1A |
| Gene ID: | 909 |
| Uniprot ID: | CD1A_HUMAN |
| Immunogen Region: | CD1a |
| Specificity: | Positive control: Skin or Langerhans cell histiocytosis X |
| Immunogen: | CD1a |
| Tissue Specificity | Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. |
| Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
| Protein Name | T-Cell Surface Glycoprotein Cd1aT-Cell Surface Antigen T6/Leu-6Hta1 Thymocyte AntigenCd Antigen Cd1a |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinMembrane RaftEndosome MembraneSubject To Intracellular Trafficking Between The Cell Membrane And EndosomesLocalizes To Cell Surface Lipid Rafts |
| Alternative Antibody Names | Anti-T-Cell Surface Glycoprotein Cd1a antibodyAnti-T-Cell Surface Antigen T6/Leu-6 antibodyAnti-Hta1 Thymocyte Antigen antibodyAnti-Cd Antigen Cd1a antibodyAnti-CD1A antibody |
Information sourced from Uniprot.org