Anti-CD194/CCR4 antibody [SAA0069] (STJA0027135)

SKU:
STJA0027135
£254.50 - £378.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-C-C Chemokine Receptor Type 4 is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0069
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CCR4
Gene ID: 1233
Uniprot ID: CCR4_HUMAN
Post Translational Modifications In natural killer cells, CCL22 binding induces phosphorylation on yet undefined Ser/Thr residues, most probably by beta-adrenergic receptor kinases 1 and 2.
Function High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Protein Name C-C Chemokine Receptor Type 4
C-C Ckr-4
Cc-Ckr-4
Ccr-4
Ccr4
K5-5
Cd Antigen Cd194
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-C Chemokine Receptor Type 4 antibody
Anti-C-C Ckr-4 antibody
Anti-Cc-Ckr-4 antibody
Anti-Ccr-4 antibody
Anti-Ccr4 antibody
Anti-K5-5 antibody
Anti-Cd Antigen Cd194 antibody
Anti-CCR4 antibody
Anti-CMKBR4 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0028499 Anti-CD194/CCR4 antibody [SAA0069] {FITC} (STJA0028499) Mouse Monoclonal Human FC
STJA0031397 Anti-CD194/CCR4 antibody [SAA0069] {PE} (STJA0031397) Mouse Monoclonal Human FC
STJA0029465 Anti-CD194/CCR4 antibody [SAA0069] {APC} (STJA0029465) Mouse Monoclonal Human FC
STJA0030431 Anti-CD194/CCR4 antibody [SAA0069] {PerCP} (STJA0030431) Mouse Monoclonal Human FC
STJA0016653 Anti-CD194/CCR4 antibody [L291H4] {APC} (STJA0016653) Mouse Monoclonal Human FC
!