Anti-CD194/CCR4 antibody [SAA0069] {PerCP} (STJA0030431)

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STJA0030431-100
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Short Description :Mouse monoclonal C-C Chemokine Receptor Type 4 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA0069
Isotype:IgG2ak
Conjugation:PerCP
Concentration:0.5 mg/mL
Purification:Purified
Formulation:PBS pH 7.4, 50% glycerol, 0.05% proclin300
Storage Instruction:Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol:CCR4
Gene ID:1233
Uniprot ID:CCR4_HUMAN
Post Translational Modifications In natural killer cells, CCL22 binding induces phosphorylation on yet undefined Ser/Thr residues, most probably by beta-adrenergic receptor kinases 1 and 2.
Function High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Protein Name C-C Chemokine Receptor Type 4
C-C Ckr-4
Cc-Ckr-4
Ccr-4
Ccr4
K5-5
Cd Antigen Cd194
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-C Chemokine Receptor Type 4 antibody
Anti-C-C Ckr-4 antibody
Anti-Cc-Ckr-4 antibody
Anti-Ccr-4 antibody
Anti-Ccr4 antibody
Anti-K5-5 antibody
Anti-Cd Antigen Cd194 antibody
Anti-CCR4 antibody
Anti-CMKBR4 antibody

Information sourced from Uniprot.org

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