Host: |
Mouse |
Applications: |
FC |
Reactivity: |
Human |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-C-C Chemokine Receptor Type 3 is suitable for use in Flow Cytometry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
5E8 |
Conjugation: |
FITC |
Isotype: |
IgG2bk |
Formulation: |
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Purification: |
Affinity purified |
Concentration: |
5 Mu L/Test |
Storage Instruction: |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
Protein Name | C-C Chemokine Receptor Type 3C C Ckr3C-C Ckr-3Cc-Ckr-3Ccr-3Ccr3Ckr 3Ckr3Eosinophil Eotaxin ReceptorCd Antigen Cd193 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 3 antibodyAnti-C C Ckr3 antibodyAnti-C-C Ckr-3 antibodyAnti-Cc-Ckr-3 antibodyAnti-Ccr-3 antibodyAnti-Ccr3 antibodyAnti-Ckr 3 antibodyAnti-Ckr3 antibodyAnti-Eosinophil Eotaxin Receptor antibodyAnti-Cd Antigen Cd193 antibodyAnti-CCR3 antibodyAnti-CMKBR3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance