Anti-CD19 antibody [HI19a] {EF700} (STJA0016518)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationEF700
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal anti-C-C Chemokine Receptor Type 3 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | HI19a |
| Isotype | IgG1k |
| Conjugation | EF700 |
| Purification | Affinity purified |
| Formulation | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction | Store between 2-8Β°C and protecting from prolonged exposure to light. Do not freeze this product. |
Target Information
| Gene Symbol | CCR3 |
| Gene ID | 1232 |
| Uniprot ID | CCR3_HUMAN |
Additional Info
| Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
| Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
| Protein Name | C-C Chemokine Receptor Type 3C C Ckr3C-C Ckr-3Cc-Ckr-3Ccr-3Ccr3Ckr 3Ckr3Eosinophil Eotaxin ReceptorCd Antigen Cd193 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 3 antibodyAnti-C C Ckr3 antibodyAnti-C-C Ckr-3 antibodyAnti-Cc-Ckr-3 antibodyAnti-Ccr-3 antibodyAnti-Ccr3 antibodyAnti-Ckr 3 antibodyAnti-Ckr3 antibodyAnti-Eosinophil Eotaxin Receptor antibodyAnti-Cd Antigen Cd193 antibodyAnti-CCR3 antibodyAnti-CMKBR3 antibody |
Information sourced from Uniprot.org