| Host: |
Armenian Hamster |
| Applications: |
FC |
| Reactivity: |
Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Armenian Hamster monoclonal antibody anti-C-X-C chemokine receptor type 3 is suitable for use in Flow Cytometry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
CXCR3-173 |
| Conjugation: |
PE |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 1% BSA |
| Concentration: |
0.2 mg/mL |
| Storage Instruction: |
Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Tissue Specificity | Expresses in lymphoid organs and Th1 cells. |
| Post Translational Modifications | Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding. N-glycosylated. |
| Function | Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. |
| Protein Name | C-X-C Chemokine Receptor Type 3Cxc-R3Cxcr-3Interferon-Inducible Protein 10 ReceptorIp-10 ReceptorCd Antigen Cd183 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 3 antibodyAnti-Cxc-R3 antibodyAnti-Cxcr-3 antibodyAnti-Interferon-Inducible Protein 10 Receptor antibodyAnti-Ip-10 Receptor antibodyAnti-Cd Antigen Cd183 antibodyAnti-Cxcr3 antibodyAnti-Cmkar3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![C57BL/6 murine splenocytes were stained with Anti-CD183/CXCR3 antibody (STJA0000684) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated). Splenocytes stained with Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated) (right) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/145537/292195/STJA0000684_1__15261.1631206039.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-CD183/CXCR3 antibody (STJA0000684) [Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated). Splenocytes stained with Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated) (right) were used as control.")