| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Cd180 antigen for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | G28-8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Concentration: | 1 mg/ml |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | CD180 |
| Gene ID: | 4064 |
| Uniprot ID: | CD180_HUMAN |
| Function | May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells. |
| Protein Name | Cd180 AntigenLymphocyte Antigen 64Radioprotective 105 Kda ProteinCd Antigen Cd180 |
| Database Links | Reactome: R-HSA-166016 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd180 Antigen antibodyAnti-Lymphocyte Antigen 64 antibodyAnti-Radioprotective 105 Kda Protein antibodyAnti-Cd Antigen Cd180 antibodyAnti-CD180 antibodyAnti-LY64 antibodyAnti-RP105 antibody |
Information sourced from Uniprot.org