Anti-CD180 antibody [G28-8] {PE} (STJA0042292)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationPE
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal anti-CD180 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | G28-8 |
| Isotype | IgG1k |
| Conjugation | PE |
| Concentration | 5 Mu L/Test |
| Formulation | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction | Store between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Target Information
| Gene Symbol | CD180 |
| Gene ID | 4064 |
| Uniprot ID | CD180_HUMAN |
Additional Info
| Tissue Specificity | Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells. |
| Function | May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells. |
| Protein Name | Cd180 AntigenLymphocyte Antigen 64Radioprotective 105 Kda ProteinCd Antigen Cd180 |
| Database Links | Reactome: R-HSA-166016 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd180 Antigen antibodyAnti-Lymphocyte Antigen 64 antibodyAnti-Radioprotective 105 Kda Protein antibodyAnti-Cd Antigen Cd180 antibodyAnti-CD180 antibodyAnti-LY64 antibodyAnti-RP105 antibody |
Information sourced from Uniprot.org