Anti-CD168/RHAMM antibody (341-440) (STJ11103496)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CD168/RHAMM (341-440) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HMMR |
| Gene ID | 3161 |
| Uniprot ID | HMMR_HUMAN |
| Immunogen Region | 341-440 |
| Immunogen Sequence | LQIDSLLQQEKELSSSLHQK LCSFQEEMVKEKNLFEEELK QTLDELDKLQQKEEQAERLV KQLEEEAKSRAEELKLLEEK LKGKEAELEKSSAAHTQATL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 341-440 of human CD168/RHAMM (NP_001136028.1). |
Additional Info
| Tissue Specificity | Expressed in testis. Expressed in the breast. |
| Function | Receptor for hyaluronic acid (HA). Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis. |
| Protein Name | Hyaluronan Mediated Motility ReceptorIntracellular Hyaluronic Acid-Binding ProteinReceptor For Hyaluronan-Mediated MotilityCd Antigen Cd168 |
| Database Links | Reactome: R-HSA-2160916Reactome: R-HSA-8854518 |
| Cellular Localisation | Cell SurfaceCytoplasmCytoskeletonSpindle |
| Alternative Antibody Names | Anti-Hyaluronan Mediated Motility Receptor antibodyAnti-Intracellular Hyaluronic Acid-Binding Protein antibodyAnti-Receptor For Hyaluronan-Mediated Motility antibodyAnti-Cd Antigen Cd168 antibodyAnti-HMMR antibodyAnti-IHABP antibodyAnti-RHAMM antibody |
Information sourced from Uniprot.org