Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | HMMR |
Gene ID: | 3161 |
Uniprot ID: | HMMR_HUMAN |
Immunogen Region: | 341-440 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 341-440 of human CD168/RHAMM (NP_001136028.1). |
Immunogen Sequence: | LQIDSLLQQEKELSSSLHQK LCSFQEEMVKEKNLFEEELK QTLDELDKLQQKEEQAERLV KQLEEEAKSRAEELKLLEEK LKGKEAELEKSSAAHTQATL |
Tissue Specificity | Expressed in testis. Expressed in the breast. |
Function | Receptor for hyaluronic acid (HA). Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis. |
Protein Name | Hyaluronan Mediated Motility ReceptorIntracellular Hyaluronic Acid-Binding ProteinReceptor For Hyaluronan-Mediated MotilityCd Antigen Cd168 |
Database Links | Reactome: R-HSA-2160916Reactome: R-HSA-8854518 |
Cellular Localisation | Cell SurfaceCytoplasmCytoskeletonSpindle |
Alternative Antibody Names | Anti-Hyaluronan Mediated Motility Receptor antibodyAnti-Intracellular Hyaluronic Acid-Binding Protein antibodyAnti-Receptor For Hyaluronan-Mediated Motility antibodyAnti-Cd Antigen Cd168 antibodyAnti-HMMR antibodyAnti-IHABP antibodyAnti-RHAMM antibody |
Information sourced from Uniprot.org