Host: | Rabbit |
Applications: | IF/ICC/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | Hmmr |
Gene ID: | 15366 |
Uniprot ID: | HMMR_MOUSE |
Immunogen Region: | 716-794 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 716-794 of mouse CD168 (NP_038580.2). |
Immunogen Sequence: | QNLKQKIKHVVKLKDENSQL KSEVSKLRSQLVKRKQNELR LQGELDKALGIRHFDPSKAF CHASKENFTPLKEGNPNCC |
Tissue Specificity | Ubiquitously expressed. |
Function | Receptor for hyaluronic acid (HA). Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenesis. |
Protein Name | Hyaluronan Mediated Motility ReceptorIntracellular Hyaluronic Acid-Binding ProteinReceptor For Hyaluronan-Mediated MotilityCd Antigen Cd168 |
Database Links | Reactome: R-MMU-2160916Reactome: -MMU-8854518 |
Cellular Localisation | Cell SurfaceCytoplasmCytoskeletonSpindle |
Alternative Antibody Names | Anti-Hyaluronan Mediated Motility Receptor antibodyAnti-Intracellular Hyaluronic Acid-Binding Protein antibodyAnti-Receptor For Hyaluronan-Mediated Motility antibodyAnti-Cd Antigen Cd168 antibodyAnti-Hmmr antibodyAnti-Ihabp antibodyAnti-Rhamm antibody |
Information sourced from Uniprot.org