Anti-CD167b/DDR2 nanobody [SAA0978] (STJN000281)

Anti-CD167b/DDR2 nanobody [SAA0978] (STJN000281)

SKU:
STJN000281
£378.50 - £1,632.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Discoidin Domain-Containing Receptor 2 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA0978
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: DDR2
Gene ID: 4921
Uniprot ID: DDR2_HUMAN
Post Translational Modifications N-glycosylated. Tyrosine phosphorylated in response to collagen binding. Phosphorylated by SRC.this is required for activation and subsequent autophosphorylation on additional tyrosine residues.
Function Tyrosine kinase involved in the regulation of tissues remodeling. It functions as a cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
Protein Name Discoidin Domain-Containing Receptor 2
Discoidin Domain Receptor 2
Cd167 Antigen-Like Family Member B
Discoidin Domain-Containing Receptor Tyrosine Kinase 2
Neurotrophic Tyrosine Kinase - Receptor-Related 3
Receptor Protein-Tyrosine Kinase Tkt
Tyrosine-Protein Kinase Tyro10
Cd Antigen Cd167b
Database Links Reactome: R-HSA-3000171
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Nanobody Names Anti-Discoidin Domain-Containing Receptor 2 nanobody
Anti-Discoidin Domain Receptor 2 nanobody
Anti-Cd167 Antigen-Like Family Member B nanobody
Anti-Discoidin Domain-Containing Receptor Tyrosine Kinase 2 nanobody
Anti-Neurotrophic Tyrosine Kinase - Receptor-Related 3 nanobody
Anti-Receptor Protein-Tyrosine Kinase Tkt nanobody
Anti-Tyrosine-Protein Kinase Tyro10 nanobody
Anti-Cd Antigen Cd167b nanobody
Anti-DDR2 nanobody
Anti-NTRKR3 nanobody
Anti-TKT nanobody
Anti-TYRO10 nanobody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP000891 Human DDR2/CD167b protein (Recombinant) (C-His) (STJP000891) HEK293 cells
STJP010047 Human CD167b/DDR2 protein (Recombinant) (N-His) (STJP010047) E. coli
STJP007104 Human CD167b/DDR2 protein (Recombinant) (C-His) (STJP007104) Mammalian Cells
STJP006676 Human CD167b/DDR2 protein (Recombinant) (C-His) (STJP006676) Mammalian Cells
STJ97997 Anti-DDR2 antibody [3B11E4] (STJ97997) Mouse Monoclonal Human WB/IHC/IF/ELISA
!