| Post Translational Modifications | Highly N- and O-glycosylated.contains sialic acid. The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain. |
| Function | Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. |
| Protein Name | Sialomucin Core Protein 24Muc-24EndolynMulti-Glycosylated Core Protein 24Mgc-24Mgc-24vCd Antigen Cd164 |
| Database Links | |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane ProteinEndosome MembraneCell MembraneIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Sialomucin Core Protein 24 antibodyAnti-Muc-24 antibodyAnti-Endolyn antibodyAnti-Multi-Glycosylated Core Protein 24 antibodyAnti-Mgc-24 antibodyAnti-Mgc-24v antibodyAnti-Cd Antigen Cd164 antibodyAnti-CD164 antibody |
Information sourced from Uniprot.org
