Host: |
Mouse |
Applications: |
FC |
Reactivity: |
Human |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-T-lymphocyte activation antigen CD80 is suitable for use in Flow Cytometry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
3G8 |
Conjugation: |
PE/Cyanine5.5 |
Isotype: |
IgG1k |
Formulation: |
PBS with 0.05% Proclin300, 1% BSA |
Storage Instruction: |
Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Tissue Specificity | Expressed on activated B-cells, macrophages and dendritic cells. |
Function | Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B. |
Protein Name | T-Lymphocyte Activation Antigen Cd80Activation B7-1 AntigenBb1Ctla-4 Counter-Receptor B7.1B7Cd Antigen Cd80 |
Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-2219530Reactome: R-HSA-389356Reactome: R-HSA-389357Reactome: R-HSA-389359Reactome: R-HSA-389513Reactome: R-HSA-6783783Reactome: R-HSA-6811558 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-T-Lymphocyte Activation Antigen Cd80 antibodyAnti-Activation B7-1 Antigen antibodyAnti-Bb1 antibodyAnti-Ctla-4 Counter-Receptor B7.1 antibodyAnti-B7 antibodyAnti-Cd Antigen Cd80 antibodyAnti-CD80 antibodyAnti-CD28LG antibodyAnti-CD28LG1 antibodyAnti-LAB7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance