Anti-CD13 antibody (69-966 aa) (STJ11105177)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CD13 (69-966 aa) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Anpep |
| Gene ID | 16790 |
| Uniprot ID | AMPN_MOUSE |
| Immunogen Region | 69-966 aa |
| Immunogen Sequence | KPWNQYRLPKTLIPDSYRVI LRPYLTPNNQGLYIFQGNST VRFTCNQTTDVIIIHSKKLN YTLKGNHRVVLRTLDGTPAP NIDKTELVERTEYLVVHLQG SLVEGRQYEMDSQFQGELAD DLAGFYRSEYMEGDVKKVVA TTQMQAADARKSFPCFDEPA MKAMFNITLIYPNNLIALSN MLPKESKPYPEDPSCTMTEF HSTPKMSTYLLAYIVSEFKN ISSVSANGVQIGIWARPSA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 69-966 of mouse CD13. (NP_032512.2). |
Additional Info
| Tissue Specificity | Expressed in the intestinal brush border (at protein level). Highly expressed in intestinal tract and kidney, present in liver, lymph node, spleen, and brain. Found as well in monocytes, macrophages, dendritic cells, veiled cells and B-cells but not on T-cells and thymocytes. |
| Post Translational Modifications | N- and O-glycosylated. Sulfated. May undergo proteolysis and give rise to a soluble form. |
| Function | Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. |
| Protein Name | Aminopeptidase NAp-NMapnAlanyl AminopeptidaseAminopeptidase MAp-MMembrane Protein P161Microsomal AminopeptidaseCd Antigen Cd13 |
| Database Links | Reactome: R-MMU-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinAlso Found As A Soluble Form |
| Alternative Antibody Names | Anti-Aminopeptidase N antibodyAnti-Ap-N antibodyAnti-Mapn antibodyAnti-Alanyl Aminopeptidase antibodyAnti-Aminopeptidase M antibodyAnti-Ap-M antibodyAnti-Membrane Protein P161 antibodyAnti-Microsomal Aminopeptidase antibodyAnti-Cd Antigen Cd13 antibodyAnti-Anpep antibodyAnti-Lap-1 antibodyAnti-Lap1 antibody |
Information sourced from Uniprot.org