• Immunohistochemistry analysis of CD13 in paraffin-embedded mouse Intestine tissue using CD13 Rabbit polyclonal antibody (STJ11105177) at a dilution of 1:900 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of CD13 in paraffin-embedded human kidney tissue using CD13 Rabbit polyclonal antibody (STJ11105177) at a dilution of 1:900 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of CD13 in paraffin-embedded rat kidney tissue using CD13 Rabbit polyclonal antibody (STJ11105177) at a dilution of 1:900 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of CD13 in paraffin-embedded mouse kidney tissue using CD13 Rabbit polyclonal antibody (STJ11105177) at a dilution of 1:900 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of CD13 in paraffin-embedded human liver tissue using CD13 Rabbit polyclonal antibody (STJ11105177) at a dilution of 1:900 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Western blot analysis of various lysates, using CD13 Rabbit polyclonal antibody (STJ11105177) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-CD13 antibody (69-966 aa) (STJ11105177)

SKU:
STJ11105177

£112.50 - £524.50
Current Stock:
Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IHC-P:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Anpep
Gene ID: 16790
Uniprot ID: AMPN_MOUSE
Immunogen Region: 69-966 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 69-966 of mouse CD13. (NP_032512.2).
Immunogen Sequence: KPWNQYRLPKTLIPDSYRVI LRPYLTPNNQGLYIFQGNST VRFTCNQTTDVIIIHSKKLN YTLKGNHRVVLRTLDGTPAP NIDKTELVERTEYLVVHLQG SLVEGRQYEMDSQFQGELAD DLAGFYRSEYMEGDVKKVVA TTQMQAADARKSFPCFDEPA MKAMFNITLIYPNNLIALSN MLPKESKPYPEDPSCTMTEF HSTPKMSTYLLAYIVSEFKN ISSVSANGVQIGIWARPSA
Tissue Specificity Expressed in the intestinal brush border (at protein level). Highly expressed in intestinal tract and kidney, present in liver, lymph node, spleen, and brain. Found as well in monocytes, macrophages, dendritic cells, veiled cells and B-cells but not on T-cells and thymocytes.
Post Translational Modifications N- and O-glycosylated. Sulfated. May undergo proteolysis and give rise to a soluble form.
Function Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity.
Protein Name Aminopeptidase N
Ap-N
Mapn
Alanyl Aminopeptidase
Aminopeptidase M
Ap-M
Membrane Protein P161
Microsomal Aminopeptidase
Cd Antigen Cd13
Database Links Reactome: R-MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Also Found As A Soluble Form
Alternative Antibody Names Anti-Aminopeptidase N antibody
Anti-Ap-N antibody
Anti-Mapn antibody
Anti-Alanyl Aminopeptidase antibody
Anti-Aminopeptidase M antibody
Anti-Ap-M antibody
Anti-Membrane Protein P161 antibody
Anti-Microsomal Aminopeptidase antibody
Anti-Cd Antigen Cd13 antibody
Anti-Anpep antibody
Anti-Lap-1 antibody
Anti-Lap1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance