Anti-CD127 antibody [R08-5I2] (STJA0034126)

SKU:
STJA0034126
£133.50 - £281.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-CD127 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R08-5I2
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: IL7R
Gene ID: 3575
Uniprot ID: IL7RA_HUMAN
Immunogen: A synthetic peptide of human CD127
Post Translational Modifications N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form. Ubiquitinated by MARCHF8.leading to lysosomal degradation.
Function Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Protein Name Interleukin-7 Receptor Subunit Alpha
Il-7 Receptor Subunit Alpha
Il-7r Subunit Alpha
Il-7r-Alpha
Il-7ra
Cdw127
Cd Antigen Cd127
Database Links Reactome: R-HSA-1266695
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Membrane
Isoform 4: Secreted
Alternative Antibody Names Anti-Interleukin-7 Receptor Subunit Alpha antibody
Anti-Il-7 Receptor Subunit Alpha antibody
Anti-Il-7r Subunit Alpha antibody
Anti-Il-7r-Alpha antibody
Anti-Il-7ra antibody
Anti-Cdw127 antibody
Anti-Cd Antigen Cd127 antibody
Anti-IL7R antibody

Information sourced from Uniprot.org