| Tissue Specificity | Spleen, thymus and fetal liver. |
| Post Translational Modifications | N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form. Ubiquitinated by MARCHF8.leading to lysosomal degradation. |
| Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| Protein Name | Interleukin-7 Receptor Subunit AlphaIl-7 Receptor Subunit AlphaIl-7r Subunit AlphaIl-7r-AlphaIl-7raCd Antigen Cd127 |
| Database Links | Reactome: R-MMU-1266695Reactome: -MMU-8856825Reactome: -MMU-8856828 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-7 Receptor Subunit Alpha antibodyAnti-Il-7 Receptor Subunit Alpha antibodyAnti-Il-7r Subunit Alpha antibodyAnti-Il-7r-Alpha antibodyAnti-Il-7ra antibodyAnti-Cd Antigen Cd127 antibodyAnti-Il7r antibody |
Information sourced from Uniprot.org
![C57BL/6 murine splenocytes were stained with Anti-Mouse CD127 Monoclonal Antibody (APC Conjugated)[Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/145109/291775/STJA0000256_1__06608.1631205561.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-Mouse CD127 Monoclonal Antibody (APC Conjugated)[Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.")
