Anti-CD109 antibody [EBS-CD-046] (STJ16101133)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenA BALB/c mouse was immunized with recombinant human CD109. Fusion partner: NS-0.
General Information
| Short Description | Mouse monoclonal anti-CD109 for use in FC, IF and IHC in Human and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC |
| Host | Mouse |
| Reactivity | Human/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | EBS-CD-046 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Flow cytometry (0, 5-1, 0 µg/million cells). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 min at RT: for staining of formalin-fixed tissues no suitable antigen retrieval method is known to date). |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Gene Symbol | CD109 |
| Gene ID | 135228 |
| Uniprot ID | CD109_HUMAN |
| Immunogen | A BALB/c mouse was immunized with recombinant human CD109. Fusion partner: NS-0. |
Additional Info
| Tissue Specificity | Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 4 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta. |
| Post Translational Modifications | N-glycosylated. 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form. |
| Function | Modulates negatively TGFB1 signaling in keratinocytes. |
| Protein Name | Cd109 Antigen150 Kda Tgf-Beta-1-Binding ProteinC3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 7Platelet-Specific Gov AntigenP180R150Cd Antigen Cd109 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Cd109 Antigen antibodyAnti-150 Kda Tgf-Beta-1-Binding Protein antibodyAnti-C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 7 antibodyAnti-Platelet-Specific Gov Antigen antibodyAnti-P180 antibodyAnti-R150 antibodyAnti-Cd Antigen Cd109 antibodyAnti-CD109 antibodyAnti-CPAMD7 antibody |
Information sourced from Uniprot.org