| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CD105 is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SM4908 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB (M) 1:500-1:1000 |
| Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: |
Eng |
| Gene ID: |
13805 |
| Uniprot ID: |
EGLN_MOUSE |
| Immunogen: |
Recombinant protein corresponding to Mouse CD105 |
| Function | Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. May play a role in the binding of endothelial cells to integrins. Acts as a TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3. |
| Protein Name | EndoglinCell Surface Mj7/18 AntigenCd Antigen Cd105 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Endoglin antibodyAnti-Cell Surface Mj7/18 Antigen antibodyAnti-Cd Antigen Cd105 antibodyAnti-Eng antibodyAnti-Edg antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
