Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
Protein Name | Intercellular Adhesion Molecule 2Icam-2Cd Antigen Cd102 |
Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083Reactome: R-HSA-5621575 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillusCo-Localizes With RdxEzr And Msn In Microvilli |
Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 2 antibodyAnti-Icam-2 antibodyAnti-Cd Antigen Cd102 antibodyAnti-ICAM2 antibody |
Information sourced from Uniprot.org