Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | Icam2 |
Gene ID: | 15896 |
Uniprot ID: | ICAM2_MOUSE |
Immunogen Region: | 20-222 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-222 of mouse CD102. (NP_034624.1). |
Immunogen Sequence: | SGEKAFEVYIWSEKQIVEAT ESWKINCSTNCAAPDMGGLE TPTNKIMLEEHPQGKWKQFL VSNVSKDTVFFCHFTCSGKQ HSESLNIRVYQPPAQVTLKL QPPRVFVGEDFTIECTVSPV QPLERLTLSLLRGRETLKNQ TFGGAETVPQEATATFNSTA LKKDGLNFSCQAELDLRPHG GYIIRSISEYQILEVYEPMQ DNQ |
Tissue Specificity | Expressed in endothelial cells and leukocytes. High levels found in lung. |
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
Protein Name | Intercellular Adhesion Molecule 2Icam-2Lymphocyte Function-Associated Ag-1 Counter-ReceptorCd Antigen Cd102 |
Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083Reactome: -MMU-5621575 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillusCo-Localizes With RdxEzr And Msn In Microvilli |
Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 2 antibodyAnti-Icam-2 antibodyAnti-Lymphocyte Function-Associated Ag-1 Counter-Receptor antibodyAnti-Cd Antigen Cd102 antibodyAnti-Icam2 antibodyAnti-Icam-2 antibody |
Information sourced from Uniprot.org