| Host: | Mouse |
| Applications: | WB/IHC/IF |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD10 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SM0418 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Purification: | Affinity purification |
| Dilution Range: | WB (M, R) 1:500-1:1000IHC/IF (M, R) 1:500-1:1000 |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | MME |
| Gene ID: | 4311 |
| Uniprot ID: | NEP_HUMAN |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CD10 |
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
| Protein Name | NeprilysinAtriopeptidaseCommon Acute Lymphocytic Leukemia AntigenCallaEnkephalinaseNeutral Endopeptidase 24.11NepNeutral EndopeptidaseSkin Fibroblast ElastaseSfeCd Antigen Cd10 |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-5578768Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Neprilysin antibodyAnti-Atriopeptidase antibodyAnti-Common Acute Lymphocytic Leukemia Antigen antibodyAnti-Calla antibodyAnti-Enkephalinase antibodyAnti-Neutral Endopeptidase 24.11 antibodyAnti-Nep antibodyAnti-Neutral Endopeptidase antibodyAnti-Skin Fibroblast Elastase antibodyAnti-Sfe antibodyAnti-Cd Antigen Cd10 antibodyAnti-MME antibodyAnti-EPN antibody |
Information sourced from Uniprot.org
![Anti-CD10 antibody [56C6] (STJ16100319)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/149037/346652/STJ16100319_1__44103.1681998728.jpg?c=1 "Anti-CD10 antibody [56C6] (STJ16100319)")
